How to Tune from Standard to Drop D Tuning

Start in standard tuning (E-A-D-G-B-E) and change 1 of 6 strings to play “Assassin”:

StringStandardTargetWhat to do
String 6E2D2Tune down a whole step
String 5A2A2Leave as is
String 4D3D3Leave as is
String 3G3G3Leave as is
String 2B3B3Leave as is
String 1E4E4Leave as is
Recommended string gauge: .010–.046. Tension stays close to standard, so a regular set works without any setup changes.Ernie Ball Regular Slinky (.010–.046) · affiliate link

Song Overview & Tuning Breakdown

"Assassin" by Muse is played in Drop D Tuning (D - A - D - G - B - E). Starting from standard tuning (E-A-D-G-B-E), you retune 1 of 6 strings: string 6 down to D. Overall string tension drops, with the biggest change being 2 semitones down. Muse uses this same tuning on 1 other song in our catalog, so you can stay tuned and keep playing.

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Tunings Close to Drop D Tuning

Already tuned to D - A - D - G - B - E? These tunings are just one small change away.

Muse’s Guitar Tunings

Muse plays 2 of 12 songs in our catalog in Drop D Tuning. Most-used tunings:

Gear for Drop D Tuning

Strings and tools that make playing "Assassin" in Drop D Tuning easier.

Ernie Ball Regular Slinky (.010–.046)

Recommended gauge .010–.046. Tension stays close to standard, so a regular set works without any setup changes.

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D'Addario Universal Micro Headstock Tuner

A headstock tuner makes switching in and out of this tuning quick, even on stage or without a mic.

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“Assassin” Tuning FAQ

What tuning is "Assassin" by Muse in?

"Assassin" is played in Drop D Tuning: D - A - D - G - B - E, from the lowest to the highest string.

How do I tune my guitar to play "Assassin"?

Start from standard tuning (E-A-D-G-B-E). String 6: tune down a whole step (E2 → D2). Leave the other strings as they are.

What string gauge should I use for Drop D Tuning?

Use a .010–.046 set. Tension stays close to standard, so a regular set works without any setup changes.

Which other Muse songs use this tuning?

"New Born" — all in D - A - D - G - B - E, so you can play them without retuning.

More Songs by Muse

Explore other guitar tunings recorded by Muse:

View all 12 songs
AADGBE TuningIntermediate
A - A - D - G - B - ENo Capo
Custom Tuning (CADGBE)Intermediate
CADGBENo Capo
Custom Tuning (BF#BF#BE)Intermediate
BF#BF#BENo Capo
Custom Tuning (CADGBE)Intermediate
CADGBENo Capo

Other Songs in Drop D Tuning

Once tuned to D - A - D - G - B - E, try playing these tracks next:

Drop D TuningIntermediate
D - A - D - G - B - ENo Capo
Drop D TuningIntermediate
D - A - D - G - B - ENo Capo
Drop D TuningIntermediate
D - A - D - G - B - ENo Capo
Drop D TuningIntermediate
D - A - D - G - B - ENo Capo
Drop D TuningIntermediate
D - A - D - G - B - ENo Capo
Drop D TuningIntermediate
D - A - D - G - B - ENo Capo
Drop D TuningIntermediate
D - A - D - G - B - ENo Capo
Drop D TuningIntermediate
D - A - D - G - B - ENo Capo