Leprosy

Required String Notes:D - G - C - F - A - D

How to Tune from Standard to D Standard / Whole-Step Down

Start in standard tuning (E-A-D-G-B-E) and change 6 of 6 strings to play “Leprosy”:

String	Standard	Target	What to do
String 6	E2	D2	Tune down a whole step
String 5	A2	G2	Tune down a whole step
String 4	D3	C3	Tune down a whole step
String 3	G3	F3	Tune down a whole step
String 2	B3	A3	Tune down a whole step
String 1	E4	D4	Tune down a whole step

Recommended string gauge: .011–.054. The bass end is slackened noticeably; a slightly heavier set keeps it tight without a full setup change.Ernie Ball Beefy Slinky (.011–.054) · affiliate link

Song Overview & Tuning Breakdown

"Leprosy" by Death is played in D Standard / Whole-Step Down (D - G - C - F - A - D). Starting from standard tuning (E-A-D-G-B-E), you retune 6 of 6 strings: string 6 down to D, string 5 down to G, string 4 down to C, string 3 down to F, string 2 down to A, string 1 down to D. Overall string tension drops, with the biggest change being 2 semitones down. Death uses this same tuning on 9 other songs in our catalog, so you can stay tuned and keep playing.

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Tunings Close to D Standard / Whole-Step Down

Already tuned to D - G - C - F - A - D? These tunings are just one small change away.

Standard E241 songs

E - A - D - G - B - ESame chord shapes, every string a whole step higher.

Drop C Tuning130 songs

C - G - C - F - A - DOnly string 6 differs: C instead of D.

Half-Step Down / Eb Standard109 songs

Eb - Ab - Db - Gb - Bb - EbSame chord shapes, every string a half step higher.

C# Standard Tuning52 songs

C# - F# - B - E - G# - C#Same chord shapes, every string a half step lower.

Death’s Guitar Tunings

Death plays 10 of 10 songs in our catalog in D Standard / Whole-Step Down. Most-used tunings:

D Standard / Whole-Step DownD - G - C - F - A - D10 songs

Gear for D Standard / Whole-Step Down

Strings and tools that make playing "Leprosy" in D Standard / Whole-Step Down easier.

Ernie Ball Beefy Slinky (.011–.054)

Recommended gauge .011–.054. The bass end is slackened noticeably; a slightly heavier set keeps it tight without a full setup change.

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D'Addario Universal Micro Headstock Tuner

A headstock tuner makes switching in and out of this tuning quick, even on stage or without a mic.

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D'Addario Pro-Winder (winder + cutter)

Retuning 6 strings means a lot of turning — a winder speeds it up and trims new strings too.

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“Leprosy” Tuning FAQ

What tuning is "Leprosy" by Death in?

"Leprosy" is played in D Standard / Whole-Step Down: D - G - C - F - A - D, from the lowest to the highest string.

How do I tune my guitar to play "Leprosy"?

Start from standard tuning (E-A-D-G-B-E). String 6: tune down a whole step (E2 → D2). String 5: tune down a whole step (A2 → G2). String 4: tune down a whole step (D3 → C3). String 3: tune down a whole step (G3 → F3). String 2: tune down a whole step (B3 → A3). String 1: tune down a whole step (E4 → D4).

What string gauge should I use for D Standard / Whole-Step Down?

Use a .011–.054 set. The bass end is slackened noticeably; a slightly heavier set keeps it tight without a full setup change.

Which other Death songs use this tuning?

"1000 Eyes", "Baptized In Blood", "Bite The Pain", "Cosmic Sea", "Crystal Mountain", "Pull The Plug" and 3 more — all in D - G - C - F - A - D, so you can play them without retuning.